What are validated self-report adherence scales really measuring?: a systematic review. Algorithms for diagnostics and treatment.
Oganov RG, Simanenkov VI, Bakulin IG, et al. Bojcov SA, Pogosova NV, Bubnova MG, et al. Pharmacotherapy in the elderly and senile age. Tkacheva ON, Kotovskaja JuV, Runihina NK, et al. Adherence to antihypertensive medication in Russia: a scoping review of studies on levels, determinants and intervention strategies published between 20. The impact of medication adherence on clinical outcomes of coronary artery disease: A meta-analysis. Improving Medication Adherence in Coronary Heart Disease. Does age modify the relationship between adherence to secondary prevention medications and mortality after acute myocardial infarction? A nested case-control study. Predictors of medication adherence in the elderly. A systematic review of barriers to medication adherence in the elderly: looking beyond cost and regimen complexity. Evidence-based strategies for the optimization of pharmacotherapy in older people. Topinkova E, Baeyens JP, Michel JP, Lang PO. A systematic review of interventions to improve medication taking in elderly patients prescribed multiple medications. Adherence to evidence-based secondary prevention pharmacotherapy in patients after an acute coronary syndrome: A systematic review. Identification and assessment of adherence-enhancing interventions in studies assessing medication adherence through electronically compiled drug dosing histories: a systematic literature review and meta-analysis. Demonceau J, Ruppar T, Kristanto P, et al. Adherence to cardiovascular therapy: a meta-analysis of prevalence and clinical consequences. Adherence to Long-term Therapies Evidence for Action. 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes. Problems of providing cardiac care for later-life patients: status and prospects. Tkacheva ON, Kotovskaya YuV, Duplyakov DV. Gerontology Issues in Cardiology Practice. Tkacheva ON, Belenkov YN, Karpov YA, Zyryanov SK. Temporal trends in ischemic heart disease mortality in 21 world regions, 1980 to 2010: the Global Burden of Disease 2010 study. Moran AE, Forouzanfar MH, Roth GA, et al. Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015. Non-adherent elderly patients cause higher load on general practitioner, supplementary pharmaceutical provision program provided no better adherence in the population under research.ġ. Among adherent patients fewer individuals smoke and mean values of lipids are lower. Medical history and structure of pharmacotherapy do not influence level of adherence in this population. Half of elderly patients with CAD are non-adherent to treatment in primary care setting. Adherent patients had lower mean values of lipids: total cholesterol (4.7☑.2 vs 5.2☑.4 mmol/l p0.05).Ĭonclusion. There were fewer smokers in adherent group (0.7% vs 6.5% p0.05). These groups were comparable in terms of sex (female 71.2 vs 68.0% p>0.05) and age (median 73.5 vs 73.0 years p>0.05) distribution, and medical history: myocardial infarction (39.0% vs 38.8%), atrial fibrillation (37.0 and 41.5%), chronic heart failure (90.4% vs 91.2%), diabetes (26.7% vs 24.5%). By means of dichotomic interpretation of Morisky scale results the population under research was divided into two groups: 147 (50.2%) non-adherent patients and 146 (49.8%) – totally adherent patients. Analysis of specific questions of the scale done in non-adherent patients revealed signs of unintentional non-adherence due to forgetfulness (45.9%) and signs of intentional non-adherence due to patients feeling worse (35.8%) or better (28.4%). According to Morisky scale high adherence was identified in 146 (49.8%) elderly patients, moderate adherence – in 99 (33.8%) patients, low adherence – in 48 (16.4%) patients. Level of medication adherence measured by Morisky scale (MMAS-8) via telephone survey. The following patient data obtained via electronic medical record system: demography, medical history, modifiable risk factors and prescribed pharmacotherapy. 293 elderly (≥65 years) patients with established CAD included.
The study conducted in out-patient clinic of Moscow city. To study medication adherence in elderly patients with coronary artery disease (CAD) in primary care practice.
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